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antibodies targeting mapk pi3k pathway components  (Cell Signaling Technology Inc)


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    Structured Review

    Cell Signaling Technology Inc antibodies targeting mapk pi3k pathway components
    Antibodies Targeting Mapk Pi3k Pathway Components, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/pathway+components/pm41222695-79-5-32
    Average 86 stars, based on 1 article reviews
    antibodies targeting mapk pi3k pathway components - by Bioz Stars, 2026-10
    86/100 stars

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    Related Articles

    other:


    Staining:

    Article Title: CRISPR Screens Reveal YAP/TEAD Axis as a Mediator of Drug-Tolerant Cells in EGFR- Mutant NSCLC
    Article Snippet: .. Parallel plates were stained using antibodies targeting MAPK/PI3K pathway components (phospho-p44/42 MAPK [E10, #9106], phospho-AKT [D9E, #4075, AF647-conjugated], phospho-S6 [D57.2, #9865, AF594-conjugated]) or Hippo pathway components (YAP1/WWTR1 [D24E4, #8418]), all from Cell Signaling Technology (Danvers, MA). ..

    Article Title: CRISPR screens reveal YAP/TEAD axis as a mediator of drug-tolerant cells in EGFR-mutant NSCLC.
    Article Snippet: Despite initial responses, most patients with metastatic lung cancer—including those with EGFR mutations—ultimately develop resistance to targeted therapies.. To systematically uncover mechanisms underlying this resistance, genome-wide CRISPR knockout and activation screens were conducted in EGFR-mutant lung cancer cell lines treated with EGFR inhibitors such as osimertinib and gefitinib.. These screens highlighted a recurrent involvement of genes associated with the Hippo signaling pathway.

    Bioprocessing:


    Expressing:

    Article Title: Comprehensive molecular profiling of combined hepatocellular carcinoma and cholangiocarcinoma reveals distinct Notch signaling subgroups with prognostic significance.
    Article Snippet: The analyzed markers included HepPar-1 (1:50, Cell Marque, Cat. No. 264M-95) and Glypican-3 (1:100, Abcam, Cat. No. AA-SSS) as HCC markers, CK7 (1:200, Dako, Cat. No. M7018) and CK19 (1:50, Cell Marque, Cat. No. 319M-15) as CCC markers, and EpCAM (1:500, Abcam, Cat. No. ab223582) and CD13 (1:200, Invitrogen, Cat. No. 14–0138-82) as stem cell markers. .. Additionally, the expression of key Notch pathway components, NOTCH1 (1:200, Cell Signaling, Cat. No. 3608S) and HES5 (1:200, BIOSS, Cat. No. BS-3767R), was assessed. ..

    Western Blot:

    Article Title: TRERNA1 upregulation mediated by HBx promotes sorafenib resistance and cell proliferation in HCC via targeting NRAS by sponging miR-22-3p.
    Article Snippet: The protein content in cell lysates was quantified using a bicinchoninic acid (BCA) protein assay kit (Beyotime, Jiangsu, China). .. Cell lysates were analyzed by immunoblot with primary antibodies specific for cell-cycle-related proteins (Cell Cycle Regulation Sampler Kit, #9932; Cell Signaling Technology [CST]), NRAS (D261977; Sangon Biotech), phospho-Erk1/2 pathway components (Phospho-Erk1/2 Pathway Sampler Kit, #9911; CST), and HRP-conjugated secondary antibodies (Sigma, USA). .. An anti-b-actin antibody (Sigma) was used as the internal reference.



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